Implications of Biofilms on Implantable Medical Devices at the 26th Annual Fall Scientific Meeting
At the first day of the 26th SMSNA Annual Fall Scientific Meeting, Dr. Aaron Miller briefly discussed the implications of biofilms on implantable medical devices.
Dr. Miller's research discovered that the origin of infectious biofilms was found to come from the host, as the subcutaneous tissue's biofilm was identical to the device's biofilm. This points to an obstacle in infection prevention: the influence of the patient's microbiome.
Comparing device materials, Dr. Miller found that bacterial count was influenced by the device manufacturer and the material used, with titanium offering the lowest risk of bacterial growth. Antibiotic use increased the abundance of known pathogens, leading to an increased risk of infection. Moving away from broad-spectrum antibiotics and creating patient-specific combinations may be useful in the future.
With further research and development, Dr. Miller believes the introduction of new materials and quorum-sensing inhibitors may be beneficial in reducing the risk of infections with implantable medical devices.
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