At the first day of the 26th SMSNA Annual Fall Scientific Meeting, Dr. Eliza Burr discussed the effects of GLP-1 and GLP-1/GIP receptor agonists on female sexual function, and in respect to age group in two subsequent studies.
Dr. Burr’s first study revealed that a quarter of participants reported changes in sexual function, with half of those reports experiencing a distressing decrease in sexuaal function. Specifically, the results showed a statistically significant decrease in the domains of desire and arousal.
The second study revealed significant decreases in sexual function in the 31–40-year-old age group, with fewer reports of sexual dysfunction as age increased. This trend appears to correlate with hormonal changes across pre-, peri-, and postmenopausal groups. Given that the decrease in sexual function was consistent across age groups in women taking GLP-1 and GLP-1/GIP receptor agonists, Dr. Burr posits that this may indicate a baseline level of sexual function among women on these medications.
Dr. Burr recommends further and more rigorous research into the effects of GLP-1 and GLP-1/GIP receptor agonists on female sexual function, as current findings remain inconsistent.